In a second attack in Cambrils, a resort town about 80 miles from Barcelona, police shot dead five people wearing fake bomb belts who plowed into a crowd with a car. A woman was killed and six people were injured.
"You will by now have heard about the tragic events today in Barcelona," the late night talk show host said, addressing his audience. "It saddens me that once again I need to start our program talking about another appalling tragedy in the world."
Mentioning the attacks in London, Paris and Stockholm, Corden acknowledged some might start becoming "numb" to the violence.
"But we think we mustn’t allow it to become something that’s normal," he urged. "We must talk about it so that we'll remember how sad, horrific and tragic these moments are.
"To the people of Spain and Barcelona, I just want to add to the rest of the world's outpouring of love and give our thoughts for you," he continued. "We are thinking about the victims and their families right now on what must be an unimaginable day of horror for them."