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St. Louis, MO (Sports Network) - Matt Holliday homered and scored twice to back seven innings of one-run ball from Kyle Lohse as the St. Louis Cardinals downed the Chicago Cubs, 4-1, in the opener of a three-game series at Busch Stadium.

Lohse (10-2) scattered six hits and a walk with four strikeouts to win his fourth straight decision. Jason Motte tossed a perfect ninth to record his 21st save of the year.

Carlos Beltran, Yadier Molina and Lance Berkman also knocked in a run for the Cardinals, who had dropped five of their last six.

Ryan Dempster (5-4) surrendered all four runs on seven hits and two walks over six innings to snap a six-start win streak.

Darwin Barney knocked in the lone run for Chicago, which had won seven of its last nine.

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