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David Jackson, USA TODAY

President Obama is about to engage in a second-term tradition -- reshuffling the Cabinet.

Secretary of State Hillary Rodham Clinton and Treasury Secretary Timothy Geithner are likely departures, and there may well be others.

Obama will also probably have to make major staff changes, as officials leave for the private sector rather than commit to another four years.

ABC's Jake Tapper looks at the state of play for the State and Treasury Department jobs:

"To replace Clinton, Democratic insiders suggest that U.S. Ambassador to the United Nations Dr. Susan Rice is the front-runner, with Sen. John Kerry, D-Mass., also a viable candidate.

"Rice has been harshly criticized by Republicans for the erroneous comments she made on Sunday news talk shows after the attack on the U.S. compound in Benghazi, Libya -- comments that were based on intelligence reports that falsely blamed the attack on a protest against an anti-Muslim video. When the president, during his recent press conference, offered a vociferous defense of Rice, many of those close to him began to suspect he was tipping his hand as to what he might decide.

"To replace Geithner at Treasury, White House chief of staff Jack Lew is thought to have the inside track if he wants it, with other possibilities including Neal Wolin, the current deputy secretary of the Treasury, and Lael Brainaed, current undersecretary of the Treasury for international affairs.

"Other informed sources suggest that there is consideration being given to a business/CEO type such as investor Roger Altman, former Time/Warner chair Richard Parsons, and Facebook's Sheryl Sandberg. ...

"If Lew leaves to take the position at Treasury, some possible replacements for him as chief of staff include deputy National Security adviser Denis McDonough or Vice President Biden's current chief of staff Ron Klain. Tom Nides, deputy secretary of state for management and resources, has also been discussed."

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