ST. LOUIS — Two motorcyclists were killed and several others were injured in a motorcycle crash early Friday morning.

Interstate 70 was shut down near Union Boulevard for several hours while police investigated the crash.

Police said five motorcycles were going west on I-70 at a "high rate of speed" when the motorcycle in the front crashed into a Dodge Nitro. That rider was pronounced dead at the hospital. 

The other motorcyclists fell as a result of the crash, and one of those riders was hit and killed by another driver.

Three other motorcycle riders were taken to the hospital for treatment.

This is a developing story and will be updated as 5 On Your Side receives more information.