A pedestrian waits to cross South Broad Street during a snowstorm in Philadelphia, Friday, Dec. 15, 2017. More wintry weather is forecast for the Northwest and central U.S. later this week.
Matt Rourke, AP

If you're traveling this week for the Christmas holiday, the main trouble spots for weather will be across portions of the South, the Northwest and Midwest. 

The ArkLaTex region into the Tennessee Valley will see heavy rain on Tuesday and Wednesday. As much as 3 to 4 inches of rain is possible, the National Weather Service predicted.

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The weather service warned of a risk for flash flooding across this region. Cities where flooding is possible include Dallas, Little Rock, Memphis and Nashville. 

Severe thunderstorms could also soak northern Mississippi, Alabama and Georgia on Wednesday.

Rain, Snow in Northwest

Meanwhile, rain and snow is forecast for the Northwest and eventually the central U.S. this week. Winter storm watches and warnings have been posted from northern California into the northern Cascades and across the northern Rockies.

That system will begin on the West Coast Tuesday, bringing rain from Seattle to San Francisco and mountain snow from the Cascades to the Sierra Range, according to ABC News meteorologist Max Golembo.

For much of the Cascades range and the Northern Rockies, upwards of a foot, maybe 2 feet, of snow is possible, the weather service said.

On Thursday, the storm will move out into the Plains, bringing heavy snow from Denver to the Twin Cities, Golembo said.

Frigid weather is coming

Later in the week, the coldest air of the season is poised to roar into the central U.S., all the way from the Rockies to the Great Lakes. 

The cold comes straight from the Arctic, weather.us meteorologist Ryan Maue said.

How cold? By Christmas Eve and Christmas Day, subzero low temperatures are likely along a broad swath from the Rockies and High Plains to the Upper Midwest and northern Great Lakes, the Weather Channel said.

The weather service is predicting a high temperature around 0 degrees for Minneapolis for Christmas Day.  In North Dakota, "dangerous," well below-zero wind chills are likely, the weather service warned.

“This cold blast may take until after Christmas to reach all of the Northeast,” AccuWeather meteorologist Brett Anderson said